ABO Blood Group and Severity of Coronary Artery Disease Assessed by Syntax Score in Patients with Acute Myocardial

Bangladesh Heart Journal Pub Date : 2022-12-28 DOI:10.3329/bhj.v37i2.63134

Md Zillur Rahman, S. Chowdhury, I. J. Shimu, P. Biswas, A. Towab, A. K. Das, Khurshadul Alam, A. Mahmud, Khondoker Al Monsur Helal

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Abstract

Introduction: As coronary artery disease (CAD) is a major cause of morbidity and mortality; timely diagnosis and appropriate therapy is of paramount importance to improve clinical outcomes. Though there are major risk factors for CAD but sometimes it does not correlate with ACS. So, search for new risk factor is necessary for better management of CAD specially STEMI. Aim: To see the association between ABO blood group and severity of CAD in patients with STEMI. Methods: This study was done during the period of January 2016 to June 2016 with STEMI at National Institute of Cardiovascular diseases, Dhaka, Bangladesh. 100 patients were grouped in I and II where group-I having 50 patients of non-O blood group and group-II having 50 patients of O blood group. After CAG all reports were analyzed by two experts and SYNTAX score were calculated and data were analyzed by SPSS. Results: Baseline characteristics (100 patients) were well matched between the groups. Low SYNTAX score (d”22) was 16% and 56%; intermediate score (23-32) was 40% and 36% and high score (>32) was 44% and 8% in group- I and group-II respectively. These indicate that patients of non-O blood group have high SYNTAX score that is more severe CAD. Univariate and multivariate regression analysis showed that non-O blood group is an independent risk factor for CAD. So easily available ABO blood grouping can be helpful to determine the severity of CAD in patients with STEMI. Bangladesh Heart Journal 2022; 37(2): 107-115

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句法评分评价急性心肌患者ABO血型与冠状动脉疾病严重程度

导论:由于冠状动脉疾病(CAD)是发病率和死亡率的主要原因;及时的诊断和适当的治疗对改善临床结果至关重要。虽然冠心病有主要的危险因素，但有时它与ACS无关。因此，寻找新的危险因素对于更好地管理冠心病特别是STEMI是必要的。目的:探讨STEMI患者ABO血型与冠心病严重程度的关系。方法:本研究于2016年1月至2016年6月在孟加拉国达卡国立心血管疾病研究所进行STEMI，将100例患者分为I和II组，其中I组有50例非O型血患者，II组有50例O型血患者。CAG结束后，所有报告由两位专家进行分析，计算SYNTAX评分，并用SPSS软件对数据进行分析。结果:基线特征(100例)组间匹配良好。低SYNTAX评分(d " 22)分别为16%和56%;中度评分(23 ~ 32分)占40%、36%，高评分(>32分)占44%、8%。提示非o型血患者SYNTAX评分高，冠心病加重。单因素和多因素回归分析显示，非o型血是冠心病的独立危险因素。因此，易于获得的ABO血型可以帮助确定STEMI患者CAD的严重程度。孟加拉国心脏杂志2022;37 (2): 107 - 115

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Bangladesh Heart Journal

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