Biochemical and laser-polarimetric markers of hepatocyte cytolysis syndrome under conditions of toxic damage and protein deficiency

Abstract

Insufficient intake of exogenous proteins under the conditions of irrational nutrition, deficiency of essential amino acids as well as increased loss of endogenous proteins with a characteristic negative nitrogen balance lead to the development of acute or chronic liver diseases. At the same time, the public availability of a wide range of drugs creates the problem of their unsystematic and irrational use for the correction of pathological conditions without proper compliance with the dosage and interval between doses. The consequence of uncontrolled self-medication is increasingly becoming drug induced liver injury.