A new method to compute T Wave Alternans

M. B. Bahreyni Toossi, A. Heydari, G. Tabatabaei Yazdi
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Abstract

The percentage of death worldwide is still the highest for cardiovascular problems. More than 50% of all cardiac deaths are due to sudden cardiac death. Despite all the work done to decrease this increasing number, identifying patients at highest risk for sudden cardiac death is still of concern. Noninvasive Microvolt T Wave Alternans test using electrocardiographic signals would be an ideal diagnostic test for stratifying the risk of sudden cardiac death in a larger group in the society. On the other hand, at present MTWA test is not reliable enough to be used for clinical decision making unless its low positive predictive value would be increased as is published by several recent studies on what should be done to save MTWA test. Another disadvantage of the present MTWA algorithms is the high number of indeterminate tests achieved. In this paper the proposed algorithm is aimed to enhance the low positive predictive value and reduce the number of indeterminate tests achieved in clinical studies.
计算T波交变的新方法
在世界范围内,心血管疾病的死亡率仍然是最高的。超过50%的心脏性死亡是由于心脏性猝死。尽管所有的工作都是为了减少这个不断增加的数字,但确定心脏性猝死风险最高的患者仍然令人担忧。使用心电图信号的无创微伏T波交替试验将是一种理想的诊断试验,可对社会上较大群体的心源性猝死风险进行分层。另一方面,目前MTWA检测还不够可靠,不能用于临床决策,除非最近几项关于如何挽救MTWA检测的研究表明,MTWA检测的低阳性预测值会增加。当前MTWA算法的另一个缺点是实现了大量的不确定测试。本文提出的算法旨在提高临床研究中低阳性预测值和减少不确定检测的数量。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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