[Side effects of the immunsuppressive cyclosporin A in dentistry].

T Braun, F Sponholz, H Sponholz
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Abstract

31 renal transplant patients with Cyclosporin-A-Medication were dental discussed. Half of the patients showed gingival hyperplasia in the anterior region of the maxilla after different time of medication. A relation between gingival hyperplasia, age and sex could'nt be seen. Two stomatitis were presented. The oral hygiene and the parodontal statement before the transplantation influenced the formation of gingival hyperplasia. At time it seems, that Nifedipin has no influence on the formation of gingival hyperplasia. We recommend a extensive research with a long list of patients. A patient with a voluminous hyperplasia was discussed.

[免疫抑制剂环孢素A在牙科中的副作用]。
对31例肾移植患者应用环孢素a治疗进行了临床分析。半数患者在用药时间不同后出现上颌前区牙龈增生。牙龈增生与年龄、性别关系不明显。2例出现口腔炎。移植前的口腔卫生和牙周状况影响牙龈增生的形成。有时,硝苯地平似乎对牙龈增生的形成没有影响。我们建议对病人进行广泛的研究。我们讨论了一个体积增生的病人。
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