Antibacterial Activities of THYMUS VULGARIS and Rifmpicin on Methicillin Resistant STAPHYLOCOCCUS AUREUS (MRSA)

Abstract

Mixtures of thyme and rifampicin were tested for inhibitory activity against 4 5 Staphylococcus aureusisolates alone and in combination. The results indicate that MICs of thyme extract mixed with rifampicin for all tested strains of S. aureus ranged between 0.2g/ml of rifampicin plus 5 mg/ml of Thyme ethyl-acetate extract or Thyme methanol extract, and 16 g/ml of rifampicin plus 6 mg/ml of Thyme ethyl-acetate extract or Thyme methanol extract. Time-killing curve of rifampicin in combination with Thyme ethyl-acetate extract and with thyme methanol extract exhibit zero CFU after 8hrs, 10hrs respectively incubation period at 37 � C that was compared with time-killing curve of rifampicin, time-killing curve of Thyme ethyl-acetate e xtract and Thyme Methanol extract