Severe bronchiolitis in children.

A L Foo, O M Chay, J Hiew, C K Tan, K W Lim, H K Cheng
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Abstract

Acute viral bronchiolitis is one of the most common causes of paediatric respiratory disease, especially in the first year of life. Young infants and those with pre-existent cardiorespiratory problems are at an increased risk of acute respiratory failure necessitating mechanical ventilation. A prospective study was carried out from November 1988 to October 1989, to analyse the clinical features, aetiology and outcome of patients with severe bronchiolitis. 52 (29.9%) out of 174 cases of acute bronchiolitis admitted were found to be severe. A virus aetiology was identified in 75% of the cases, respiratory syncytial virus (RSV) being the commonest agent. 88.5% of the patients were less than 1 year of age, with a male preponderance of 1.4:1. There was a higher incidence in the Malay ethic group. Despite the viral aetiology, 88.2% were treated with a course of antibiotics. There was one death, and 2 patients had apnea requiring mechanical ventilation.

儿童严重毛细支气管炎。
急性病毒性细支气管炎是小儿呼吸系统疾病的最常见原因之一,特别是在生命的第一年。年幼的婴儿和那些先前存在心肺问题的人在急性呼吸衰竭的风险增加,需要机械通气。从1988年11月至1989年10月进行了一项前瞻性研究,分析了重症细支气管炎患者的临床特征、病因学和转归。174例急性细支气管炎中52例(29.9%)为重症。75%的病例病原学鉴定为病毒,呼吸道合胞病毒(RSV)是最常见的病原体。88.5%的患者年龄小于1岁,男性占比1.4:1。马来族的发病率更高。尽管是病毒性病因,88.2%的患者接受了一个疗程的抗生素治疗。1例死亡,2例呼吸暂停需要机械通气。
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