Serological Evaluation of the Response of Nigerian Dogs to Flury (Lep) Vaccine

Abstract

Blood samples were taken from a total of 140 dogs that have been vaccinated against rabies at least 15 days earlier and from some that have received anti-rabies vaccine for more than once. A rapid fluorescent focusing inhibition test (RFFIT) was carried out to measure the level of neutralizing antibody (SN) in the blood of these dogs. Result showed that only 54.3% of the dogs have adequate SN titre and therefore could be considered immuned. Dogs, 19 months old and above responded more to immunization than dogs of lower age groups. Keyword: Rabies, vaccine serum neutralizing antibodies, flury LEP Trop. Vet. Vol. 21 (2) 15-20 (2003)