Eye Cancers at the Guinness Eye Center Onitsha, Nigeria

S. Nwosu, Chinasa Nnubia, C. Akudinobi
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Abstract

Objectives: To describe the hospital incidence and pattern of ocular and adnexal cancers at the Guinness Eye Center, Onitsha. Materials and Methods: The case files of all new patients seen with ocular and adnexal tumors at the Guinness Eye Center, Onitsha, between 2005 and 2017 were reviewed. Those with histological diagnosis of malignancy were selected and analyzed. Information obtained included age, sex, disease duration, diagnosis and co-morbidity. Results: There were 85 patients (0.1% of all the new patients), made up of 42 males and 43 females. The median age was 5 years; range: 5 months–70 years. The commonest cancers were retinoblastoma, 45 patients (52.9%) and conjunctival squamous cell carcinoma, 30 (35.3%). Twenty eight (93.3%) squamous cell carcinoma patients were HIV-positive. No child had squamous cell carcinoma. All retinoblastoma patients were aged ≤6 years. Conclusions: The incidence of ocular and adnexal cancers at the Guinness Eye Center, Onitsha, was low with retinoblastoma and conjunctival squamous cell carcinoma accounting for most of the cancers. While retinoblastoma would most likely be suspected in a child with ocular tumor, young adults with squamous cell carcinoma should be evaluated for HIV infection. Since these lesions threaten sight and life, the public should be educated on the early signs of the diseases and the need to report to hospital early.
尼日利亚奥尼沙吉尼斯眼科中心的眼癌
目的:描述奥尼察健力士眼科中心眼部和附件癌的医院发病率和模式。材料与方法:回顾2005年至2017年在Onitsha健力士眼科中心(Guinness Eye Center)新见的所有眼部和附件肿瘤患者的病例档案。选择组织学诊断为恶性肿瘤的患者进行分析。获得的信息包括年龄、性别、病程、诊断和合并症。结果:85例患者(占所有新患者的0.1%),其中男性42例,女性43例。中位年龄为5岁;范围:5个月- 70年。最常见的肿瘤为视网膜母细胞瘤45例(52.9%),结膜鳞状细胞癌30例(35.3%)。28例(93.3%)鳞状细胞癌患者hiv阳性。没有孩子有鳞状细胞癌。所有视网膜母细胞瘤患者年龄≤6岁。结论:在奥尼沙吉尼斯眼科中心,眼部和附件癌的发病率较低,其中视网膜母细胞瘤和结膜鳞状细胞癌占大多数。虽然视网膜母细胞瘤最有可能在患有眼部肿瘤的儿童中被怀疑,但患有鳞状细胞癌的年轻人应该评估是否感染了HIV。由于这些病变威胁到视力和生命,应教育公众了解疾病的早期迹象,并尽早到医院报告。
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