Development of Rapid and Highly-Sensitive Biosensing Systems

Abstract

This article reviews the rapid detection of the biomarkers and discrimination of the specific surface antigen expressed on living cells based on the manipulation technique of particles and cells by dielectrophoresis and the sensitive detection of products generated by an enzyme reaction with chemical amplification system. The manipulation of particles and cells improves rapidity and simplicity for the immunosensing. The sensitivity (limit of detection) for immunoassay is enhanced by the chemical amplification systems.