Schiff Bases and Their Metallic Derivatives: Highly Versatile Molecules with Biological and Abiological Perspective

M.K.I. Khan, S. Gul, M. Khan
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引用次数: 5

Abstract

1998 onwards, a span reporting thousands of research articles describes the ever-increasing applicability of Schiff bases and their metallic complexes; this chapter comprehensively examines the literature of the last 20 years. The structural diversity of these molecules made them available for a very wide range of biological and abiological applications. Schiff bases are excellent chelators and due to this unique property have found their place in qualitative and quantitative determina-tion of metals in aqueous media. The structural diversity of metal chelates proved these to be outstanding catalysts and displayed interesting fluorescence effect. Finally, Schiff base moieties have found a unique position during the in vitro and in vivo experiments for drug development against a huge number of biological enti-ties including bacteria, fungi, cancer cells, viruses, parasites, etc.
希夫碱及其金属衍生物:具有生物学和非生物学视角的高度通用分子
1998年起,一篇报道了数千篇研究文章的文章描述了希夫碱及其金属配合物日益增长的适用性;本章全面考察了近20年来的文献。这些分子的结构多样性使它们可用于非常广泛的生物和非生物应用。希夫碱是一种优良的螯合剂,由于其独特的性质,在水介质中金属的定性和定量测定中占有重要的地位。金属螯合物的结构多样性证明了它们是很好的催化剂,并表现出有趣的荧光效应。最后,希夫碱基在体外和体内实验中发现了独特的地位,用于针对大量生物实体(包括细菌、真菌、癌细胞、病毒、寄生虫等)的药物开发。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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