Antimicrobial Effects of Ethanol, Methanol and Ethyl Acetate Teucrium polium and Citrullus colocynthis extract on Pseudomonas aeruginosa

Laleh Shahraki-Mojahed, R. Behzadmehr, Zahra Beigomi
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引用次数: 8

Abstract

Pseudomonas aeruginosa is a common pathogen in a wide range of infections, from urinary tract infections to bacteremia. Intrinsic resistance to antimicrobial agents in this bacterium worsens the condition of the treatment of infections caused by it. The aim of this study was to investigate the antimicrobial effects of ethanol, methanol, and ethyl acetate Teucrium polium Extract and Citrullus colocynthis on a p. aeruginosa isolated from Zabol hospital. P. aeruginosa specimens were collected from Zabol city. Plant extracts were prepared using a rotary machine and the minimum inhibitory concentration and minimum trace concentration were determined by microdilution method. The lowest inhibitory concentration of methanolic extract of C. colocynthis against p. aeruginosa was 1.25 mg / ml while the lowest inhibitory concentration of ethyl acetate extract of C. colocynthis was 0.62 mg / ml, two strains were inhibited in this concentration and the highest inhibitory concentration was 5 mg, 6 strains of bacteria in this concentration has been restrained. The results of this study showed that watermelon extract of T. polium Extract and C. colocynthis have a significant antibacterial effect. Extract from this plant can be used to deal with specific pathogenic bacteria.
乙醇、甲醇和乙酸乙酯提取物对铜绿假单胞菌的抑菌作用
铜绿假单胞菌是一种常见的病原体在广泛的感染,从尿路感染到菌血症。这种细菌对抗菌剂的内在耐药性恶化了由它引起的感染的治疗条件。本研究旨在探讨乙醇、甲醇和乙酸乙酯提取物和瓜泥对Zabol医院分离的铜绿假单胞菌的抑菌作用。铜绿假单胞菌标本采集于Zabol市。采用旋转机提取植物提取物,用微量稀释法测定最小抑菌浓度和最小痕量浓度。对铜绿假单胞菌甲醇提取物的最低抑菌浓度为1.25 mg / ml,乙酸乙酯提取物的最低抑菌浓度为0.62 mg / ml,在该浓度下抑制了2株细菌,最高抑制浓度为5 mg,在该浓度下抑制了6株细菌。本研究结果表明,西瓜提取物、西瓜提取物和西瓜多糖均具有明显的抗菌作用。这种植物的提取物可用于处理特定的致病菌。
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