[Perioperative chemotherapy of stomach cancer].

P Preusser, H Wilke, U Fink, H J Meyer, H Bünte, J R Siewert
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Abstract

Surgery is the treatment of choice in early stages of gastric carcinoma. Systemic chemotherapy (CTx) is indicated in unresectable and metastatic disease. New studies have shown that CTx perioperatively improved median survival times compared with surgery alone in locally advanced, technically inoperable tumors. Moreover CTx induced resectability in 47-80% of the patients. Therefore, younger patients in these stages of disease should be treated with effective CTx, such as EAP, in order to induce objective remissions so that residual tumor masses can be surgically removed.

【胃癌围手术期化疗】。
手术是早期胃癌的首选治疗方法。全身化疗(CTx)适用于不可切除和转移性疾病。新的研究表明,在局部晚期、技术上不能手术的肿瘤中,围手术期CTx比单纯手术能提高中位生存时间。此外,47-80%的患者可切除CTx。因此,在这些疾病阶段的年轻患者应接受有效的CTx治疗,如EAP,以诱导客观缓解,以便手术切除残留的肿瘤块。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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