Theo Husby, M. Valic, Y. Hiraishi, Nicholas Bernards, F. Yokote, Juan Chen, G. Zheng, K. Yasufuku, Brian Wilson, R. Weersink
{"title":"Measuring in vivo Dissociation Kinetics of Porphysome Nanoparticles Using Diffuse Reflectance and Quantitative Fluorescence Spectroscopy","authors":"Theo Husby, M. Valic, Y. Hiraishi, Nicholas Bernards, F. Yokote, Juan Chen, G. Zheng, K. Yasufuku, Brian Wilson, R. Weersink","doi":"10.1364/omp.2023.ow1e.6","DOIUrl":null,"url":null,"abstract":"A combination diffuse reflectance and quantitative fluorescence spectroscopy system developed for measuring concentrations of intact and dissociated states of porphysome theranostic nanoparticles is compared to pre-clinical ex vivo PET measurements and in vivo dissociation kinetics.","PeriodicalId":111173,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)","volume":"63 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1364/omp.2023.ow1e.6","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
A combination diffuse reflectance and quantitative fluorescence spectroscopy system developed for measuring concentrations of intact and dissociated states of porphysome theranostic nanoparticles is compared to pre-clinical ex vivo PET measurements and in vivo dissociation kinetics.