S A Prokofjev, N L Perelygin, N B Dmitrijeva, E V Markina, B S Utesev
{"title":"[Studies of the immunostimulating properties of lipopolysaccharides and dextran sulfate based on a model of radiogenic immunodepression].","authors":"S A Prokofjev, N L Perelygin, N B Dmitrijeva, E V Markina, B S Utesev","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>At a model of initial immunoresponse of mice to sheep erythrocytes the immunostimulating activity of lipopolysaccharide (LPS) and dextransulphate (DS) was tested. It was shown, that suppression of the immunosystem after influence of radiation can be compensated successfully by application of lipopolysaccharide and dextransulphate. The prophylactic application of these preparation is more ineffective.</p>","PeriodicalId":76404,"journal":{"name":"Radiobiologia, radiotherapia","volume":"31 3","pages":"247-55"},"PeriodicalIF":0.0000,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Radiobiologia, radiotherapia","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
At a model of initial immunoresponse of mice to sheep erythrocytes the immunostimulating activity of lipopolysaccharide (LPS) and dextransulphate (DS) was tested. It was shown, that suppression of the immunosystem after influence of radiation can be compensated successfully by application of lipopolysaccharide and dextransulphate. The prophylactic application of these preparation is more ineffective.