PImMS: A self-triggered, 25ns resolution monolithic CMOS sensor for Time-of-Flight and Imaging Mass Spectrometry

10th IEEE International NEWCAS Conference Pub Date : 2012-06-17 DOI:10.1109/NEWCAS.2012.6329065

I. Sedgwick, A. Clark, J. Crooks, R. Turchetta, L. Hill, J. John, A. Nomerotski, R. Pisarczyk, M. Brouard, S. H. Gardiner, E. Halford, J. Lee, M. Lipciuc, C. Slater, C. Vallance, E. Wilman, B. Winter, W. Yuen

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引用次数: 7

Abstract

In this paper, we present the Pixel Imaging Mass Spectrometry (PImMS) sensor, a pixelated Time-of-Flight (TOF) sensor for use in mass spectrometry. The device detects any event which produces a signal above a programmable threshold with a timing resolution of 25ns. Both analogue and digital readout modes are available and all pixels can be individually trimmed to improve noise performance. The pixels themselves contain analogue signal conditioning circuitry as well as complex logic totalling more than 600 transistors. This large number can be achieved without any loss of quantum efficiency thanks to the use of the patented Isolated N-well Monolithic Active Pixels (INMAPS) process. In this paper, we examine the design of the PImMS 1.0 device and its successor PImMS 2.0, a significantly enlarged sensor with several added features. We will also present some initial results from mass spectrometry experiments performed with PImMS 1.0.

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一种自触发，25ns分辨率单片CMOS传感器，用于飞行时间和成像质谱

在本文中，我们提出了像素成像质谱(PImMS)传感器，一种用于质谱分析的像素化飞行时间(TOF)传感器。该设备检测任何事件产生的信号高于可编程阈值的时间分辨率为25ns。模拟和数字读出模式都是可用的，所有像素都可以单独修剪，以提高噪声性能。像素本身包含模拟信号调理电路以及总共600多个晶体管的复杂逻辑。由于使用了专利的隔离n阱单片有源像素(INMAPS)工艺，可以在不损失量子效率的情况下实现如此大的数量。在本文中，我们研究了PImMS 1.0器件及其继任者PImMS 2.0的设计，PImMS 2.0是一个显着扩大的传感器，具有几个附加功能。我们还将介绍用PImMS 1.0进行的质谱实验的一些初步结果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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10th IEEE International NEWCAS Conference

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