{"title":"On the possibility of regulatory influence of SSRs in Glycine Max (L.) Merr","authors":"A. Penzin, P. D. Timkin","doi":"10.47813/rosnio-ii.2023.8.69-72","DOIUrl":null,"url":null,"abstract":"This paper discusses the possibility of regulating gene expression by microsatellites of the non-coding part of DNA. The analysis of known SSRs from the \"soybase\" database for possible manifestation as enhancers has been carried out, since the determination of mechanisms for increasing the expression of certain genes is an important agricultural task. The SSRs analysis was carried out in the open web resource \"iEnchancer 2L\". As a result, it was revealed that some microsatellites are theoretically capable of being enhancers, an additional study showed that the sequences identified as enhancers have specific binding sites for transcription factors, which can be considered an indirect confirmation of the results obtained. The conducted studies can help to further work on the search for regulatory DNA sites, as well as advance in understanding the significance of the non-coding part of DNA.","PeriodicalId":298635,"journal":{"name":"II All-Russian (national) scientific conference with international participation \"Russian Science, Innovation, Education\"","volume":"1 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"II All-Russian (national) scientific conference with international participation \"Russian Science, Innovation, Education\"","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.47813/rosnio-ii.2023.8.69-72","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
This paper discusses the possibility of regulating gene expression by microsatellites of the non-coding part of DNA. The analysis of known SSRs from the "soybase" database for possible manifestation as enhancers has been carried out, since the determination of mechanisms for increasing the expression of certain genes is an important agricultural task. The SSRs analysis was carried out in the open web resource "iEnchancer 2L". As a result, it was revealed that some microsatellites are theoretically capable of being enhancers, an additional study showed that the sequences identified as enhancers have specific binding sites for transcription factors, which can be considered an indirect confirmation of the results obtained. The conducted studies can help to further work on the search for regulatory DNA sites, as well as advance in understanding the significance of the non-coding part of DNA.