Severe main bronchus obstruction due to pulmonary schwannoma: A Case Report

Ahmad Shirinzadeh, R. Ershadi, A. Amouei, J. Jafari, H. Soltani, S. Kargar, F. Binesh
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Abstract

Pulmonary schwannoma is a rare neoplasm that arises from peripheral nerve sheath, Schwann cells, in the lungs and mostly remains asymptomatic for months. This report presents a seven-year-old female patient with an occasional cough and fever. She was hospitalized due to the lack of response to outpatient treatments, including antibiotics and antifebrile. A biopsy was taken from the mass by bronchoscopy, and the pathology report indicated the presence of a low-grade spindle cell, Verocay body, and Antoni B areas. Based on the pathologic findings, immunohistochemical (IHC) analysis was requested. The results indicated diffusely positive for S-100 protein, and accordingly, the diagnosis of schwannoma was confirmed. Thoracotomy and lobectomy were performed. Tracheobronchial schwannoma can be treated with surgical resection or bronchoscopy.
肺神经鞘瘤所致严重主支气管阻塞1例
肺神经鞘瘤是一种罕见的肿瘤,起源于周围神经鞘,雪旺细胞,在肺部,大多数情况下数月无症状。本文报告一位七岁女病人,偶有咳嗽及发烧。由于对包括抗生素和退烧药在内的门诊治疗缺乏反应,她住院治疗。通过支气管镜对肿块进行活检,病理报告显示存在低级别梭形细胞、Verocay体和Antoni B区。根据病理结果,要求进行免疫组化(IHC)分析。结果提示S-100蛋白弥漫性阳性,诊断为神经鞘瘤。行开胸、肺叶切除术。气管支气管神经鞘瘤可通过手术切除或支气管镜检查治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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