EXTRACTION, ISOLATION AND PURIFICATION OF VARIOUS COMPONENTS OF CASSIA UNIFLORA AND IT’S IN VITRO STUDIES

Sowmya, S. Ahmed, S. Sameer, P. Polireddy, K. Dutt
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Abstract

Cassia species are one among the plants to possess great therapeutical value due to their wide rage of pharmacological activities. Hence, in our present study, we have isolated the extract of Cassia uniflora and isolated some important constituents using various solvents among which methanolic extract was optimal. The isolated compounds were also characterized by mass and IR spectroscopy. The extract was further checked for anti-oxidant as well as anti-diabetic activity. From the results obtained, the leaves and fruit extract were found to have good alpha-glucosidase as well as 5-lipoxygenase inhibition.
决明子各成分的提取、分离纯化及体外研究
决明子具有广泛的药理活性,是具有重要药用价值的植物之一。因此,在本研究中,我们对决明子的提取物进行了分离,并采用不同的溶剂对其重要成分进行了分离,其中甲醇提取物的提取效果最佳。通过质谱和红外光谱对分离得到的化合物进行了表征。进一步检测了提取物的抗氧化和抗糖尿病活性。结果表明,其叶和果提取物具有良好的α -葡萄糖苷酶和5-脂氧合酶抑制作用。
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