Efficiency of 22 online databases in the search for physicochemical, toxicological and ecotoxicological information on chemicals.

M. Guerbet, G. Guyodo
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引用次数: 4

Abstract

The objective of this study was to evaluate the efficiency of 22 free online databases that could be used for an exhaustive search of physicochemical, toxicological and/or ecotoxicological information about various chemicals. Twenty-two databases with free access on the Internet were referenced. We then selected 27 major physicochemical, toxicological and ecotoxicological criteria and 14 compounds belonging to seven different chemical classes which were used to interrogate all the databases. Two indices were successively calculated to evaluate the efficiency with taking or not taking account of their specialization. More than 50% of the 22 databases 'knew' all of the 14 chemicals, but the quantity of information provided is very different from one to the other and most are poorly documented. Two categories clearly appear with specialized and non-specialized databases. The HSDB database is the most efficient general database to be searched first, because it is well documented for most of the 27 criteria. However, some specialized databases (i.e. EXTOXNET, SOLVEDB, etc.) must be searched secondarily to find additional information.
22个在线数据库在化学物理化、毒理学和生态毒理学信息检索中的效率。
本研究的目的是评估22个免费在线数据库的效率,这些数据库可用于对各种化学品的物理化学、毒理学和/或生态毒理学信息进行详尽的搜索。参考了互联网上免费提供的22个数据库。然后,我们选择了27个主要的物理化学、毒理学和生态毒理学标准和14个化合物,属于7个不同的化学类别,用于查询所有数据库。在考虑和不考虑专业化的情况下,先后计算了两个指标来评价效率。在22个数据库中,超过50%的数据库“知道”所有14种化学物质,但是所提供的信息量各不相同,而且大多数数据库的记录都很差。专业数据库和非专业数据库明显分为两类。HSDB数据库是首先搜索的最有效的通用数据库,因为它对27个标准中的大多数都有很好的记录。但是,某些专门的数据库(即EXTOXNET、SOLVEDB等)必须进行二次搜索才能找到额外的信息。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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