Utilization of nano-hydroxyapatite mixed with platelet rich fibrin for reconstruction of severe atrophied over pneumatized maxilla: A case report

Gustavo Helder Vinholi, Igor da Silva Brum, Renan Lana Devita, João Carlos Lopes Amorim, Marco Antônio Alencar de Carvalho, J. D. de Carvalho
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Abstract

Introduction: With the current need for large bone reconstructions due to very robust losses in skeletal architecture, not only of the maxillary and mandibular regions but also in other regions of the body, this guided bone regeneration has been increasingly used. Case Report: A leukoderma patient at 52 years of age sought the implantology clinic of the Brazilian Dental Association (ABO) to solve his case of tooth loss. The patient presented overly aggressive bone loss in the total maxilla, and, because of this, it was planned to reconstruct the lost area with a synthetic particulate nano-biomaterial (Blue Bone, Curitiba, Brazil), with the help of the platelet aggregate (PRF). For the surgery, 6 grams of this biomaterial were used, in the anterior region of the maxilla, tent screws were placed to stabilize the grafted bilateral and maxillary sinus lifting surgeries were performed in the posterior regions. The entire regenerated area was covered with L-PRF membrane for better stability and healing. An incredibly significant gain in bone volume was observed six months after surgery throughout the regenerated region, enabling the placement of dental implants (Systhex, Curitiba, Brazil) and later the placement of the supported prosthesis. Conclusion: The nano graft presented a very favorable result in the gain of bone volume, proving to be an excellent indication for more severe cases of bone loss.
应用纳米羟基磷灰石混合富血小板纤维蛋白重建严重萎缩过气上颌1例
导言:由于骨骼结构的严重损失,目前需要大量的骨重建,不仅是上颌和下颌区域,而且在身体的其他区域,这种引导骨再生已经越来越多地使用。病例报告:一位52岁的白癜病患者到巴西牙科协会(ABO)的种植诊所寻求解决他牙齿脱落的病例。患者表现为全上颌骨骨质流失过于严重,因此,计划在血小板聚集体(PRF)的帮助下,使用合成颗粒纳米生物材料(Blue bone, Curitiba, Brazil)重建丢失的区域。在手术中,使用了6克这种生物材料,在上颌前区放置帐篷螺钉以稳定移植的双侧,并在后区进行上颌窦提升手术。整个再生区域被L-PRF膜覆盖,以获得更好的稳定性和愈合。术后6个月观察到整个再生区域的骨体积显著增加,这使得植入牙种植体(Systhex, Curitiba, Brazil)和随后的支撑假体植入成为可能。结论:纳米移植物在骨体积的增加方面有很好的效果,对于更严重的骨丢失病例是一个很好的指征。
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