Corticosteroid Withdrawal in Vascularized Composite Allotransplantation

J. Diaz-Siso, S. Fischer, Geoffroy C. Sisk, E. Bueno, S. Talbot, M. Carty, F. Marty, B. Pomahac, S. Tullius
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Abstract

Steroid avoidance in immunosuppression regimes after solid organ transplantations is feasible without hindering graft outcome or introducing complications. In vascular composite tissue allotransplantations (VCA), however, discharge of steroids is treated with caution, due to the various types of tissues involved and the associated belief of high immunogenicity of skin. In this study we present our experience with steroid withdrawal in 5 VCA recipients.
血管化复合异体移植中皮质类固醇的停用
在实体器官移植后免疫抑制机制中避免类固醇是可行的,不会影响移植结果或引入并发症。然而,在血管复合组织异体移植(VCA)中,由于涉及多种类型的组织以及相关的皮肤高免疫原性,类固醇的排出需要谨慎处理。在这项研究中,我们介绍了5例VCA受者类固醇戒断的经验。
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