{"title":"Evading Evasion","authors":"Mostafa Mohammed Elsabagh","doi":"10.15173/sciential.v1i1.1910","DOIUrl":null,"url":null,"abstract":"The CRISPR-Cas9 system has paved the way for realizing gene-editing, but its main weakness lies in its potential for off-target effects. Studies into phages reveal that they express “anti-CRISPR” proteins which if harnessed, could provide us with the solution to this lack of control.","PeriodicalId":262888,"journal":{"name":"Sciential - McMaster Undergraduate Science Journal","volume":"41 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2018-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Sciential - McMaster Undergraduate Science Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15173/sciential.v1i1.1910","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The CRISPR-Cas9 system has paved the way for realizing gene-editing, but its main weakness lies in its potential for off-target effects. Studies into phages reveal that they express “anti-CRISPR” proteins which if harnessed, could provide us with the solution to this lack of control.