Study on Active Components on Sleep-Improving Function of Compound Prescription of Valeriana Officinalis

Abstract

In this paper, Experiments were carried out on mice with valerian complexes(Valerian officinal is, Ziziphus jujuba Mill. Var. Spinosa (Bunge), platycladi seed), detection of its active components to improve sleep. Direct sleep experiment method as the evaluation index to discuss effects of sedative and sleeping of valerian extract water, valerian compound prescription and their respective extraction component. Valerian aqueous extract, compound preparation, valerian extract and ethyl acetate extract phase and the water extract of nbutanol extraction phase can Being shorten the sleep latency of mice, prolong the sleeping time of mice, no tolerance. The nbutanol extract of Valerian a water phase to shorten the sleep latency of mice, it is the best effect to prolong the sleeping time of mice.