Transradial Approach

Abstract

Objective To evaluate the effect and safety of clopidogrel plus tiro-fi ban in percutaneous coronary intervention (PCI) of acute myocardial infarction via transradial approach. Methods A total of 104 patients with ST segment elevation myocardial infarction who were underwent emergency PCI were randomised into two groups: clopidogrel combined tiro fi ban group (n ¼ 48) and clopidogrel group (n ¼ 56). Bolus tiro fi ban (10 m g/kg) was infused in 3 min before PCI and then 0.15 m g/kg/min continued pumping for 24 h in the clopidogrel combined tiro fi ban group, while saline was used in the same way in the clopidogrel group. The TIMI fl ow grade in IRA before PCI, after the fi rst guide wire getting through and instant post-PCI were recorded and compared between the two groups. The myocardial blush grade post-PCI and heart function were analysed and compared between the two groups. Hemorrhagic complications and MACE in-hospital were monitored and followed up. Results The