Prevalence and correlates of peripheral neuropathy amongst type 2 diabetes mellitus patients – A community-based epidemiological study in a town of Eastern India

S. Chakraborty, A. Majumder
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Abstract

Background: Diabetic peripheral neuropathy (DPN) is a microvascular complication of type 2 diabetes mellitus (T2DM) which may be attributed to chronic uncontrolled hyperglycaemia. DPN increases the risk of foot ulcers and non traumatic amputations, leading to disability, morbidity and poor quality of life for the diabetics. Aims: This study aims to find out the prevalence of peripheral neuropathy amongst T2DM patients and ascertain the correlates for the same. Settings and Design: A cross sectional study was conducted amongst 104 diabetic individuals of Bankura city of West Bengal using principles of simple random sampling technique. Materials and Methods: Data on peripheral neuropathy were collected using Michigan Neuropathy Screening Instrument and correlates were assessed by a pre designed pre tested schedule consisting of background and socio demographic characteristics along with medication adherence rating scale. Statistical Analysis Used: Data were entered into Excel (Microsoft Inc.) and all calculations were done using IBM Statistical Package for the Social Sciences (SPSS) (Version 20.0, IBM). Data were analysed and presented using principles of descriptive and analytical statistics. Results: The prevalence of DPN was 59.1%. The presence of co morbidities, poor socio economic status, polypharmacy, food insecurity, catastrophic health expenditure and lack of social insurance were found significantly associated with DPN. Conclusions: DPN prevalence was found to be considerably high. Multiple factors were found to culminate it, upon which socio economic and health care affordability issues were prominent. A multi disciplinary approach focusing on them using Patients oriented evidence that matters approach, diabetes education and periodic screening of the diabetic population may help in mitigating the morbidity risks.
2型糖尿病患者周围神经病变的患病率及相关因素——印度东部城镇社区流行病学研究
背景:糖尿病周围神经病变(DPN)是2型糖尿病(T2DM)的微血管并发症,可能归因于慢性不受控制的高血糖。DPN增加足部溃疡和非创伤性截肢的风险,导致糖尿病患者残疾、发病率和生活质量下降。目的:本研究旨在了解T2DM患者周围神经病变的患病率,并确定其相关因素。背景与设计:采用简单随机抽样方法,对西孟加拉邦班库拉市104名糖尿病患者进行横断面研究。材料和方法:使用密歇根神经病变筛查仪收集周围神经病变的数据,并通过预先设计的预测试时间表评估相关因素,该时间表包括背景和社会人口学特征以及药物依从性评定量表。使用统计分析:数据输入Excel (Microsoft Inc.),所有计算使用IBM Statistical Package for the Social Sciences (SPSS) (Version 20.0, IBM)完成。使用描述性和分析性统计原理对数据进行分析和呈现。结果:DPN患病率为59.1%。合并症的存在、社会经济地位低下、多种药物、粮食不安全、灾难性的卫生支出和缺乏社会保险被发现与DPN显著相关。结论:DPN的患病率相当高。多种因素导致了这一现象,其中社会经济和医疗负担能力问题尤为突出。多学科的方法关注他们,采用以患者为导向的重要证据方法,糖尿病教育和糖尿病人群的定期筛查可能有助于减轻发病风险。
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