Primary Ciliary Dyskinesia

Abstract

*Corresponding author. E-mail address: miguel.armengot@gmail.com (M. Armengot Carceller). Abstract Primary ciliary dyskinesia is a genetically inherited syndrome characterised by ciliary immotility or dysmotility. Deficiency in mucociliary clearance produces chronic respiratory infections from birth, male sterility by spermatozoid immotility and situs inversus in 40%-50% of patients (Kartagener’s syndrome). Diagnosis is made by analysing ciliary motility with high-speed digital video and ciliary ultrastructure. The wide distribution and functions of the cilia in the body mean that this dysfunction can generate other ciliopathies apart from primary ciliary dyskinesia. © 2008 Elsevier España, S.L. All rights reserved.