Unilateral exudative retinal detachment as the first manifestation of lung carcinoma

Thamarai Munirathinam, Pei Fang Neoh
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Abstract

Background: Exudative retinal detachment without ocular metastasis is extremely rare.Case presentation: We report a case of sudden onset of painless vision loss in the left eye with relative afferent pupillary defect. Fundus features suggested exudative retinal detachment. Abnormal cutaneous findings and lung findings led to the suspicion of malignancy. Computed tomography of the brain and orbit showed no ocular metastasis; however, imaging of thorax, abdomen and pelvis revealed lung malignancy with distant metastasis. Immunohistochemistry profile of the skin biopsy was suggestive of metastatic adenocarcinoma.Conclusion: A high index of suspicion, thorough physical examination and prompt intervention can be lifesaving.
单侧渗出性视网膜脱离为肺癌的首发表现
背景:无眼部转移的渗出性视网膜脱离极为罕见。病例介绍:我们报告一例突然发作的无痛性视力丧失在左眼相对传入瞳孔缺损。眼底特征提示渗出性视网膜脱离。皮肤和肺部的异常表现导致怀疑为恶性肿瘤。颅脑及眼眶ct未见眼部转移;然而,胸部,腹部和骨盆的影像学显示肺部恶性肿瘤并远处转移。皮肤活检的免疫组织化学特征提示转移性腺癌。结论:高度怀疑、彻底体检、及时干预可挽救生命。
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