Morpholine-Based Novel Ionic Liquid for Synthesis and Characterization of Triazolidinethiones and Their Biological Properties

Abstract

Keeping the green chemistry approach in mind we have synthesized a novel morpholine-based ionic liquid [NBMMorph]⁺Br^-. The structure of Ionic liquid was confirmed by spectral techniques viz. IR, ¹H NMR, and ¹³C NMR, analysis. The synthesized novel IL [NBMMorph]⁺Br^- was utilized to prepare 1,2,4-triazolidine-3-thiones of biological significance. The [NBMMorph]⁺Br^- IL shows excellent catalytic activity, and a simple filtration technique can separate the thiazolidinedione products. The structure of the synthesized compounds were confirmed using IR and NMR techniques. All the synthesized compounds were screened for their antimicrobial activity. All compounds shows outstanding biological activity.