Effect of Insulin Resistance on Left Ventricular Remodeling in Essential Hypertensives: A Cross Sectional Study

Abstract

In clinical practice, left ventricular hypertrophy is defined not by the left ventricular walls thickness, but by the left ventricular mass. The later is calculated according to the Devereux's formula, and is increased by insulin resistance/hyperinsulinemia. It is however unclear which of insulin resistance, hyperinsulinemia, or both is actually causative and what is their collective or individual influence on the components of Devereux's formula and parameters of left ventricular diastolic function. Thepresent study evaluated the associations ofthe Homeostatic Model Assessment for Insulin Resistance (HOMAIR) and fasting plasma insulinwith components of Devereux's formula and parameters of left ventricular diastolic function.