Γ

Τρίγκας Μάριος, Παπαδόπουλος Ιωάννης, ταλός Γεώργιος, Καραγκούνη, Γλυκερία, Σιδεράς Αδαμάντιος, Ονουφρίου Αντρέας
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引用次数: 0

Abstract

Coronavirus disease 2019 (COVID-19) is characterized by a pro-inflammatory state associated with organ failure, thrombosis, and death. We investigated a novel inflammatory biomarker, γ ′ fibrinogen (GPF), in 103 hospitalized patients with COVID-19 and 19 healthy controls. We found significant associations between GPF levels and the severity of COVID-19 as judged by blood oxygen saturation (SpO 2 ). The mean level of GPF in the patients with COVID-19 was significantly higher than in controls (69.8 (95 % CI 64.8 – 74.8) mg/dL compared with 36.9 (95 % CI 31.4 – 42.4) mg/dL, p < 0.0001), whereas C-reactive protein (CRP), lactate dehydrogenase (LDH)
2019冠状病毒病(COVID-19)的特征是与器官衰竭、血栓形成和死亡相关的促炎状态。我们在103名住院的COVID-19患者和19名健康对照者中研究了一种新的炎症生物标志物γ '纤维蛋白原(GPF)。我们发现通过血氧饱和度(spo2)判断GPF水平与COVID-19严重程度之间存在显著相关性。COVID-19患者GPF的平均水平显著高于对照组(69.8 (95% CI 64.8 - 74.8) mg/dL与36.9 (95% CI 31.4 - 42.4) mg/dL相比,p < 0.0001),而c反应蛋白(CRP)、乳酸脱氢酶(LDH)、乳酸脱氢酶(CRP)、乳酸脱氢酶(LDH)的浓度明显高于对照组。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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