Inhibition of Formalin Induced Paw Edema in Rats by Various Fractions/Extracts of Bryophyllum pinnatum

R. Gupta, M. Lohani, R. Vishwakarma
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Abstract

Traditionally, Bryophyllum pinnatum is used in the management of arthritis and inflammatory diseases. However, B. pinnatum has not been analysed previously for anti-inflammatory activity. Hence, this study is designed to determine the anti-inflammatory effects of various fractions of B. pinnatum leaf extract using rat model of formalin-induced paw edema. Treatment with various fractions showed marked decrease in formalin-induced paw volume and edema in rats. The results of BPAAF treatment were comparable to standard drug, diclofenac. These results indicate that B. pinnatum could be developed as ant-inflammatory drug after further studies.
不同部位提取物对福尔马林所致大鼠足跖水肿的抑制作用
传统上,青叶被用于关节炎和炎症性疾病的治疗。然而,在此之前,还没有分析过雀稗的抗炎活性。因此,本研究旨在利用福尔马林致大鼠足跖水肿模型,研究白刺叶提取物不同部位的抗炎作用。各组分处理均能显著降低福尔马林所致大鼠足部体积和水肿。BPAAF治疗的结果与标准药物双氯芬酸相当。这些结果表明,经过进一步的研究,可以开发成抗炎药。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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