J M Morales González, J I González-Montalvo, T Del Ser Quijano, F Bermejo Pareja
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引用次数: 0
Abstract
Although in the last decade the screening test of dementia have improved, is still being of interest the study of simple methods with a most sensitivity and specificity in the detection of the cognitive decline. Jorm et al have used recently a questionnaire (IQCODE) by which a subject's relative informs of the decline suffered by this in his cognitive capacity. In this work is showed a spanish adaptation of this test, the spanish-IQCODE, analysing it's usefulness for the detection of mild dementia. The S-IQCODE shows a diagnostic validity (sensitivity of 86%, specificity of 92%, positive predictive value of 54% and negative predictive value of 98%) greater than Mini-Mental State Examination (MMSE); it also shows a correlation with the diagnostic of dementia greater (r = 0.70 vs r = 0.37); and, different from MMSE, it doesn't show significative correlations with the age, the schooling and the premorbid intelligence. The results in this study show the S-IQCODE as a good test for the detection of the mild dementia, of greater diagnostic power than the MMSE and less contaminated than this by strange variables to the cognitive decline.
虽然在过去的十年中,痴呆症的筛查试验已经有所改善,但在检测认知能力下降方面,研究最敏感和最特异性的简单方法仍然是人们感兴趣的。Jorm等人最近使用了一份问卷(IQCODE),通过该问卷,受试者的亲属告知其认知能力因此而下降。在这项工作中,展示了该测试的西班牙语改编,西班牙语- iqcode,分析了它对轻度痴呆检测的有用性。S-IQCODE的诊断效度(敏感性86%,特异性92%,阳性预测值54%,阴性预测值98%)高于简易精神状态检查(MMSE);它还显示与痴呆诊断的相关性更大(r = 0.70 vs r = 0.37);与MMSE不同,它与年龄、学校教育和病前智力没有显著相关。本研究结果表明,S-IQCODE是一种检测轻度痴呆的良好方法,其诊断能力比MMSE更强,而且受认知能力下降的陌生变量的影响比MMSE更小。