Herpes Simplex Virus I Infection Complicating Pemphigus Foliaceus

Abstract

Pemphigus is a group of autoimmune blistering disease characterised by blisters affecting the skin and or mucosae. Herpes simplex virus (HSV) 1 is known to result in recalcitrant oral lesions of pemphigus. It is rarely described in association with pemphigus foliaceus. Here, we describe a middle aged man who had persistent erosions on the face despite adequate disease control in other body parts. Screening for secondary infection yielded HSV-1 by polymerase chain reaction.