Measurement of Weak Low Frequency Electromagnetic Field Effects on Cells

Abstract

The aim of our research is a development of an automated experimental platform for identification of the effects of weak low frequency (LF) electromagnetic field (EMF) on cells. The platform comprises multiple measurement stations, allowing monitoring and subsequent characterization of cell cultures. Main detection approaches include the methods of electroimpedance spectroscopy (EIS), optical microscopy, and turbidimetry. EIS provides information about cell culture growth and enables electrical characterization of cell structures. Morphology and cell kinetics are investigated via computer analysis of images obtained from video-microscopy. The complex measurement system allows efficient scanning of frequencies and amplitudes of EMF while searching for possible specific response of investigated biosystem. The developing platform aspires to contribute towards general methodology of investigation into LF EMF biological effects.