Detection, Investigation and Analysis of 63 Hormone Components in Local Children Skin Care Related Products

Abstract

Objective Using the optimized method in the technical specification for 《Safety technical specifications for cosmetics 》(2015 Edition), market research was conducted on the addition of 63 prohibited hormone components in the locally marketed products claiming to have skin care effect on children (including cosmetics, class I medical devices and disinfection and sanitation products).Methods Using a column of Shimadzu shim pack XR ODS Ⅲ (2.0 × 150mm, 2.2 μm) , after gradient elution with water acetonitrile as mobile phase, 63 prohibited components were detected by ultra performance liquid chromatography-mass spectrometry (UPLC -MS). Results 63 hormone components were detected in 125 batches of children skin care related products on the market, and none of them was detected. Conclusion The market status of 63 hormone components in the local children cosmetics market is relatively good.