NITROSYL FERREDOXINES MIMETICS AS PHOSPHODIESTERASE INHIBITORS: SYNTHESIS, STRUCTURE AND ACTIVITY IN VITRO

N. Sanina
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Abstract

The paper presents and discusses experimental data on the synthesis, study of the structure and properties in the solid phase and in solutions of new low-molecular-weight iron dinitrosyl complexes with N,S-ligands of the 1,2,4 -1-H-triazole N,S-ligands of the“g = 2.03” family, nitric oxide (NO) donors, and effective inhibitors of cGMP phosphodiesterases.
模拟亚硝基铁氧多酚作为磷酸二酯酶抑制剂:体外合成、结构和活性
本文介绍并讨论了新型低分子量铁二硝基配合物的合成、固相和溶液中结构和性质的研究,这些配合物具有1,2,4 -1- h -三唑N, s -“g = 2.03”家族N, s -配体、一氧化氮(NO)供体和有效的cGMP磷酸二酯酶抑制剂。
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