Simulation and analysis of respiratory disorders of the premature infant

Abstract

Premature infants very often suffer from respiratory disorders, and respiratory system failure is a major cause of fatality during infancy. An effective simulation model of the respiratory system can be a helpful tool in early and correct assessment of the neonate's respiratory distress. The purpose of this paper is to examine the response of a simulation model of the newborn infant's respiratory system. This model, whose performance has been successfully tested on healthy newborns under different physiological conditions, is used to predict respiratory responses of premature infants showing early signs of respiratory distress. Responses of the model have been illustrated in hypoxia and air breathing, as well as under supplemental oxygen treatment.