Lessons learnt from the Plasmodium vivax MSP1 towards malaria control and elimination efforts

Abstract

Methodology: The quantification and genotyping of parasite based on MSP1 haplotypes using the new generation sequencing and comparison with a haplotype-specific serology against a broad set of Block 2 PvMSP1 peptides. The humoral response based on isotype, subclass and avidity profiles against a set of recombinant proteins PvMSP1, such as MSP1-19, N-terminal PvMSP1 and set of Block 2 PvMSP1 variants.