Multidisciplinary approach in the management of pregnancy and rheumatic diseases – the challenges for obstetricians and gynecologists

Никола Поповски, Аспарух Николов, Тихомир Тотев
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Abstract

Rheumatic diseases (RD) primarily affect young women of reproductive age and therefore pregnancy in these patients requires more attention. Pregnancy in women with RD requires a multidisciplinary, carefully coordinated approach before, during and after pregnancy to ensure the best possible prognosis for the mother and the baby. Treatment of patients with RD during pregnancy and in the post-natal period may be a major challenge for both rheumatologists and obstetrics-gynaecologists. Risk stratification and pregnancy planning are key to ensuring normal pregnancy in women with RD and minimal risk of complications. On the other hand, the risks to the fetus are related to the activity of the mother's disease, presence of specific autoantibodies, and mother's therapy. It is of great importance to stabilize the disease, to replace the medication with pregnancy-compatible drugs, tests of the autoantibody status and organ damage assessment. For these reasons, active monitoring of pregnant women with RD should be carried out by rheumatologist and gynecologist.
妊娠和风湿病管理的多学科方法——妇产科医生面临的挑战
风湿病(RD)主要影响育龄的年轻妇女,因此这些患者的妊娠需要更多的关注。RD患者的妊娠需要在妊娠前、妊娠期间和妊娠后采取多学科、精心协调的方法,以确保母亲和婴儿的最佳预后。妊娠期和产后RD患者的治疗可能是风湿病学家和妇产科医生面临的主要挑战。风险分层和妊娠计划是确保RD患者正常妊娠和将并发症风险降至最低的关键。另一方面,对胎儿的风险与母亲疾病的活动性、特异性自身抗体的存在和母亲的治疗有关。稳定病情、采用与妊娠相适应的药物替代用药、检测自身抗体状态和评估器官损害是十分重要的。因此,风湿病医生和妇科医生应对妊娠RD患者进行积极监测。
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