A New Hope for Cancer Therapy with Liquid Knife & Immuno Therapy: UMIPIC

Baofa Yu
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Abstract

Recent years cancer immunological therapy is getting very popular and many new drug have been approved by FDA like PD1 and PDl-1, however, in clinical practice of cancer treatment, it looks very limited efficacy for advanced cancer, so that physician started to use comprehensive plan by combination chemotherapy with PD1 as a novel strategy with a better clinical benefit. Since chemotherapy always produce the side effect like loss hair, vomit and neutropenia. Because of the extremely toxic side effects, many cancer patients cannot successfully complete a complete course of chemotherapy, and some even die from the side effects of chemotherapy due to a patient’s poor tolerance. The extreme side effects of anti-cancer drugs are often caused by the poor target specificity of such drugs regarding the tumor in the patient’s body. The drugs circulate through most normal organs of patients as well as the intended target tumors (less than 5% of the drug reach the tumor), while over 95% of the drug circulates through the whole body of the patient.
利用液体刀和免疫疗法治疗癌症的新希望UMIPIC
然而,在癌症治疗的临床实践中,PD1 和 PDl-1 对晚期癌症的疗效非常有限,因此医生开始采用联合化疗与 PD1 的综合方案,作为一种临床疗效更好的新策略。由于化疗总是会产生脱发、呕吐和中性粒细胞减少等副作用。由于化疗的毒副作用极大,许多癌症患者无法顺利完成一个完整的化疗疗程,有些患者甚至因耐受性差而死于化疗副作用。抗癌药物的极端副作用通常是由于这些药物对患者体内肿瘤的靶向特异性差造成的。药物在病人的大部分正常器官和目标肿瘤中循环(只有不到 5%的药物到达肿瘤),而 95%以上的药物在病人全身循环。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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