Hyperthyroidism associated with intraocular pressure and dry eye

Abstract

Graves’ orbitopathy/ophthalmopathy (GO) also known as thyroid eye disease (TED),dysthyroid/thyroid-associated ophthalmopathy (TAO), is an autoimmune disorder representing thecommonest and most important extrathyroidal manifestation of Graves’ disease. Materials andMethods: This is a prospective study conducted for 2 years. A total of 60 established cases ofHyperthyroidism of all Age groups with either gender subjects who were diagnosed with Thyroidorbitopathy at hospitals were included in this study. History of ocular surgery or medications, thosedemonstrating the recent use of contact lenses, pregnant or lactating women. All the cases withsimilar presentation not proved to be Thyroid Orbitopathy and patients who did not report for thefollow-up were excluded from the study. Result: A total of 60 patients were examined. Of the 60cases analyzed, female preponderance was noted and 41-60 years age group had the highestincidence of thyroid orbitopathy. The most common presentation was found to be unilateral. Inferiorrectus muscle was the commonest muscle involved with 48.3% followed by Medial rectus muscle38.3%, Superior rectus muscle 23.3%, and Lateral rectus muscle involved least with 11.6% indescending order. None of the patients reported a loss of vision. Conclusions: Dry eye andincreased IOP have commonly seen outcomes that should be managed diligently. This potentialsight-threatening condition is seen worldwide and has many functional and cosmetic consequencesthat need to be recognized. Hyperthyroidism was significantly associated with the severity.