Methods of optical tomography in biomedicine

Abstract

Results of the research carried out at the Institute of Applied Physics US (IAP RAS) in collaboration with the Nizhny Novgorod Medical Academy are presented. The obtained data demonstrate capabilities of Optical Coherence Tomography (OCT), Polarization-Sensitive OCT (PS OCT), and Optical Coherence Microscopy (OCM) for biomedicine. Also we present our first results on Frequency-Domain Optical Diffusion Tomography (FD ODT) and Frequency-Domain Fluorescence Diffusion Tomography (FD FDT). OCT, CP OCT and OCT are high-resolution (3- 15 mcm) techniques used for visualization of near surface objects (at depths up to 2 mm). ODT and FDT have lower resolution (4-8 mm), but they allow investigation at depths up to 5-10 cm.