Bone Mineralisation

Abstract

The mineralisation term mentions the development of inorganic precipitation over an organic background. This process occurs in a life span of biological organ-ism for the formation of bone, teeth, exoskeletons, egg shells, etc. So, basically bone mineralisation is defined as the process of deposition of minerals on the bone matrix for the development of bone. The human bone is made up of 60–70% minerals which include calcium phosphate in the form of hydroxyapatite followed by 20–40% organic matrix containing type I collagen fibres and less than 5% of water and lipids. During bone mineralisation process osteoblasts which are also known as bone forming cells, aids to the production of calcium phosphate crystals which are then aligned in the collagen based fibrous matrix. The bone mineralisation proce-dure also known as calcification is a lifelong activity of a human being.