Screen-Printed Sensor for Chloride Quantification in Sweat for Early Determination of Cystic Fibrosis

Abstract

One-use screen-printed sensor capable to generate sweat and measure the chloride concentration is presented. Sweat is induced by iontophoresis, pilocarpine is forced to get into de skin and stimulate the sweat glands. Chloride concentration is measured by potentiometry. The performance of the devices has been tested by means of reproducibility studies. Finally, the application of these sensors in several volunteers has been carried out. Errors less than 10% have been obtained in real samples.