Heat Transfer Rates Mapping in The Brain based on DSC-MRI

Abstract

The Heat Transfer Rate (HTR) of tissue is a major problem in controlling the brain tissue temperature under laser therapy to remove a tumor. For the planning, Planning, according to research (7), to set HTR of the brain tissue provides the result of the cerebral blood flow (CBF) by applying the tissue residue curves of dynamic susceptibility in contrast to magnetic resonance imaging (DSC-MRI) with gadolinium (Gd). The research created a map of heat transfer for every temperature level for brain tissue CBF by studying the samples of Glioblastoma and Meningioma tissues in the two HTR diagrams. This research, studied five sample patients by using perfusion of multiple lesions diffuse enhancement (n = 1), irregular enhancement (n = 1), and ring enhancement( n = 3). The perfusion rate from CBF of the samples was compared with the database. The result, of the HTR value HTR, at a brain tissue temperature of 34°C to 43 °C had the same result as from the analysis of the tumor; HTR increases around the rim of the tumor while the value inside is low. Another result was the HTR inside the tumor was high, while the HTR at the rim was low. The HTR data could be used to simulate tissue under the equation of bio-heat transfer.