Molecular and Phenotypic Characteristics of 16S rRNA Methylase-producing Gram-negative Bacilli

Abstract

Recently a novel plasmid-mediated re-sistant mechanism that conferred high-level resist-ance to aminoglycoside via methylation of 16S rRNA was reported. The aims of this study were to de-termine the prevalence of the 16S rRNA methylase genes and to characterize the coresistance to other antibiotics in Gram-negative bacilli.