Role of Polyphenols in Preventing Prostate Cancer Cell Growth by Calcium Channel Blockers: A Review

Abstract

Prostate cancer (PCa) is the second most widely diagnosed cancer in men and the sixth leading cause of cancer death. Signal transductions are always linked with cancers, and phytochemicals play a predominantly striking role in chemo preventions.  We specifically focused on the researches which have been done in last twenty year by using different search engines including Google Scholar, PubMed, Web of Sciences and Scopus. An increasing number of studies have looked into the role of polyphenols on prostate cancer cell growth, highlighting their ability to target various cellular mechanisms. In this review, we picked out and found the potential role of polyphenols in targeting prostate cancer through calcium channel blockers and concluded that polyphenols are the primary chemo-preventive agents for prostate cancer. Copyright(c) The Author