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Cystatin C versus creatinine-based GFR formula in CKD patients

BANTAO Journal Pub Date : 2015-02-02 DOI:10.2478/bj-2014-0007
Z. Abrishami, M. Mahdavi-Mazdeh, F. Minoo, Monireh Amerian
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Abstract

Abstract Introduction. Glomerular Filtration Rate (GFR) is the main tool to assess kidney function. Some experts suggest cystatin C as a more precise and accurate indicator than creatinine to calculate GFR. This study is designed to assess if cystatin C is more helpful in early diagnosis and better follow-up of Chronic Kidney Disease (CKD) patients who may benefit more from appropriate and timely management. Methods. We studied 312 patients in different stages of CKD and normal kidney function as control. GFR based on creatinine (Jaffe and enzymatic) and cystatin C were calculated and compared. Results. A total of 146(46.8%) patients were male with a mean age of 53±17.5 years. The patients were divided into 3 groups based on GFR (>60 cc/min/1.73m 2, 30< GFR<60cc/min/1.73m 2, 15
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慢性肾病患者胱抑素C与肌酐为基础的GFR公式
摘要介绍。肾小球滤过率(Glomerular Filtration Rate, GFR)是评估肾功能的主要工具。一些专家建议胱抑素C作为比肌酐更精确和准确的指标来计算GFR。本研究旨在评估胱抑素C是否更有助于慢性肾脏疾病(CKD)患者的早期诊断和更好的随访，这些患者可能从适当和及时的管理中获益更多。方法。我们研究了312例不同阶段的CKD患者，并以肾功能正常为对照。计算并比较基于肌酐(Jaffe和酶)和胱抑素C的GFR。结果。男性146例(46.8%)，平均年龄53±17.5岁。根据GFR将患者分为3组(> 60cc/min/1.73 3m 2, 30< GFR<60cc/min/1.73 3m 2, 15
本文章由计算机程序翻译，如有差异，请以英文原文为准。
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BANTAO Journal
BANTAO Journal
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