1. Challenges in Systems Epidemiology in Cancer

Abstract

Systems epidemiology is a new research discipline that seeks to integrate pathways analyses into observational study designs to improve the understanding of biological processes in human organisms as time-dependent changes or trajectories of functional genomics. This chapter guides the reader on the different aspects of the book. The aim is to improve the understanding of the structures of data from complex study designs, data handling, new statistical methods and the interpretation of the results.