Thoughts on the Dose-effect Correlation of Chinese Medicine

Abstract

Objective: To explore the relationship between dose and efficacy of traditional Chinese medicine, to provide reference for the study of Chinese medicine dose and toxic medicine attenuated efficiency. Methods: Through the study on Chinese medicine dose effect relationship and access to the previous use of traditional Chinese medicine to grasp the dose, summed up the Chinese medicine dose effect relationship law. Results: The dose-effect relationship of different Chinese medicines varied greatly. Some Chinese medicines showed good linear relationship within a certain dose range, while others had no obvious dose-effect relationship. Conclusion: The relationship between dosage and effect of traditional Chinese medicine should be carefully grasped, especially toxic traditional Chinese medicine, which has narrow safety range and should be monitored in real time. Keywords—toxic Chinese medicine; dose effect relationship; attenuated and synergistic effects